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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/44663

Relationship between oral cancer and implants: clinical cases and systematic literature review

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Abstract

The use of implants for oral rehabilitation of edentulous spaces has recently been on the increase, which has also led to an increase in complications such as peri-implant inflammation or peri-implantitis. Chronic inflammation is a risk factor for developing oral squamous cell carcinoma (OSCC). Objectives: To review the literature of cases that associate implant placement with the development of oral cancer. Study design: We present two clinical cases and a systematic review of literature published on the relationship between oral cancer and implants. Results: We found 13 articles published between the years 1996 and 2009, referencing 18 cases in which the osseointegrated implants are associated with oral squamous cell carcinoma. Of those, 6 articles were excluded because they did not meet the inclusion criteria. Of the 18 cases reported, only 7 cases did not present a previous history of oral cancer or cancer in other parts of the body. Conclusions: Based on the review of these cases, a clear cause-effect relationship cannot be established, although it can be deduced that there is a possibility that implant treatment may constitute an irritant and/or inflammatory cofactor which contributes to the formation and/or development of OSCC.

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Podeu consultar la versió en castellà a http://hdl.handle.net/2445/135800

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JANÉ SALAS, Enric, et al. Relationship between oral cancer and implants: clinical cases and systematic literature review. Medicina Oral. Patología Oral y Cirugia Bucal. Vol.  2012, num. 17, pags. 1. ISSN 1698-4447. [consulted: 16 of August of 2026]. Available at: https://hdl.handle.net/2445/44663

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