Fitxers
Tipus de document
ArticleVersió
Versió publicadaData de publicació
Tots els drets reservats
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/119034
Exuberant complex metaplastic carcinoma of the breast with sox2 expression: covering the full spectrum of ductal neoplasia of the breast
Títol de la revista
Director/Tutor
ISSN de la revista
Títol del volum
Recurs relacionat
Resum
We report a unusual case of a 45-year-old woman with a massive metaplastic carcinoma of the breast with a complex admixture of components including giant pleomorphic cells, sarcomatoid areas, cysts with undifferentiated stratified epithelium, squamous carcinoma foci, high grade comedo-type ductal carcinoma in situ, high grade invasive carcinoma not otherwise specified (NOS) and foci with osseous differentiation. An extensive immunohistochemical panel showed expression of both epithelial and mesenchymal markers. The self-renewal marker SOX2 was expressed in different cell types, which was interpreted as a sign of the pluripotency what can in turn explain the diversity of histologic lineages present in this tumour.
Matèries
Matèries (anglès)
Citació
Citació
SAGASTA, Amaia, et al. Exuberant complex metaplastic carcinoma of the breast with sox2 expression: covering the full spectrum of ductal neoplasia of the breast. Revista Española de Patología. 2014. Vol. 48, num. 170-175. ISSN 1699-8855. [consulted: 9 of September of 2026]. Available at: https://hdl.handle.net/2445/119034