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2012-07-24

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cc by (c) Molina et al., 2012
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/126565

Ventilatory support in critically ill hematology patients with respiratory failure

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https://doi.org/10.1186/cc11438

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Introduction: Hematology patients admitted to the ICU frequently experience respiratory failure and require mechanical ventilation. Noninvasive mechanical ventilation (NIMV) may decrease the risk of intubation, but NIMV failure poses its own risks. Methods: To establish the impact of ventilatory management and NIMV failure on outcome, data from a prospective, multicenter, observational study were analyzed. All hematology patients admitted to one of the 34 participating ICUs in a 17-month period were followed up. Data on demographics, diagnosis, severity, organ failure, and supportive therapies were recorded. A logistic regression analysis was done to evaluate the risk factors associated with death and NIVM failure. Results: Of 450 patients, 300 required ventilatory support. A diagnosis of congestive heart failure and the initial use of NIMV significantly improved survival, whereas APACHE II score, allogeneic transplantation, and NIMV failure increased the risk of death. The risk factors associated with NIMV success were age, congestive heart failure, and bacteremia. Patients with NIMV failure experienced a more severe respiratory impairment than did those electively intubated. Conclusions: NIMV improves the outcome of hematology patients with respiratory insufficiency, but NIMV failure may have the opposite effect. A careful selection of patients with rapidly reversible causes of respiratory failure may increase NIMV success.

Matèries

Unitats de cures intensives, Malalties de l'aparell respiratori, Malalties hematològiques

Matèries (anglès)

Intensive care units, Respiratory organs diseases, Blood diseases

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Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

Citació

MOLINA, Rosario, BERNAL, Teresa, BORGES, Marcio, ZARAGOZA, Rafael, BONASTRE, Juan, GRANADA, Rosa, RODRIGUEZ BORREGÁN, Juan carlos, NUÑEZ, Karla, SEIJAS, Iratxe, AYESTARAN, Ignacio, ALBAICETA, Guillermo m., EMEHU study investigators. Ventilatory support in critically ill hematology patients with respiratory failure. _Critical Care_. 2012-01-01. Vol. 16, núm. R133. [consulta: 28 de gener de 2026]. [Disponible a: https://hdl.handle.net/2445/126565]

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