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Treball de fi de grau

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cc-by-nc-nd (c) López, 2021
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/180829

Functional Connectivity Analysis of Stem Cell Cultures with Parkinson’s Disease

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We studied the activity and functional network characteristics of neurons derived from human induced pluripotent stem cells (iPSCs) grown in culture. The cells were obtained from healthy and Parkinson’s–affected patients. Using a network perspective, different magnitudes were analyzed to demonstrate connectivity and activity differences between healthy controls, diseased Parkinson’s cultures, and genetically cured ones. We unveiled an excess of integration and a loss of both modularity and small–worldness for Parkinson’s diseased cultures. The study may help the medical society to better understand the disease and develop efficient therapies

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Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2021, Tutor: Jordi Soriano Fradera

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LÓPEZ POYATOS, Ana. Functional Connectivity Analysis of Stem Cell Cultures with Parkinson’s Disease. [consulta: 29 de gener de 2026]. [Disponible a: https://hdl.handle.net/2445/180829]

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