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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/180829
Functional Connectivity Analysis of Stem Cell Cultures with Parkinson’s Disease
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We studied the activity and functional network characteristics of neurons derived from human induced pluripotent stem cells (iPSCs) grown in culture. The cells were obtained from healthy and Parkinson’s–affected patients. Using a network perspective, different magnitudes were analyzed to demonstrate connectivity and activity differences between healthy controls, diseased Parkinson’s cultures, and genetically cured ones. We unveiled an excess of integration and a loss of both modularity and small–worldness for Parkinson’s diseased cultures. The study may help the medical society to better understand the disease and develop efficient therapies
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Treballs Finals de Grau de Física, Facultat de Física, Universitat de Barcelona, Curs: 2021, Tutor: Jordi Soriano Fradera
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LÓPEZ POYATOS, Ana. Functional Connectivity Analysis of Stem Cell Cultures with Parkinson’s Disease. [consulted: 15 of October of 2026]. Available at: https://hdl.handle.net/2445/180829