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varo2017_2849.pdf (428.55 KB)

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2017-12-18

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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/119067

Leukoerythroblastosis in a Young Child with Severe Malaria and Superimposed Gram Negative Infection

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Recurs relacionat

http://dx.doi.org/10.1093/tropej/fmx101

Resum

Background: Leukoerythroblastosis, a non-specific and often short-lasting response of the bone marrow to different diseases such as malignancies or infections, is characterized by the presence in the peripheral blood of immature red and white cells. Methods: We present a case of leukoerythoblastosis occurring in a 24 months old Mozambican girl, in the context of a severe malaria episode and an associated urinary tract infection. Peripheral blood smear was used for diagnosis of malaria and leukoerythroblastosis. Enterobacter cloacae isolation and antibiotic susceptibility testing were performed by conventional microbiology. Results: Peripheral blood smear was positive for Plasmodium falciparum and showed a leukoerythroblastosis with red cell anisopoikilocytosis and left shifted neutrophils. Urine culture confirmed the presence of a multi-resistant E. cloacae. Treatment of underlying conditions resolved the leukoerythroblastic reaction. Conclusions: Leukoerythroblastosis may be related to different infectious diseases and may also appear in the context of severe malaria. Bacterial superinfection needs to be investigated.

Matèries

Malària, Malalties bacterianes

Matèries (anglès)

Malaria, Bacterial diseases

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Articles publicats en revistes (ISGlobal)

Citació

VARO, Rosauro, et al. Leukoerythroblastosis in a Young Child with Severe Malaria and
                Superimposed Gram Negative Infection. Journal of Tropical Pediatrics. 2017. ISSN 0142-6338. [consulted: 15 of August of 2026]. Available at: https://hdl.handle.net/2445/119067

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