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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/119067
Leukoerythroblastosis in a Young Child with Severe Malaria and Superimposed Gram Negative Infection
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Background: Leukoerythroblastosis, a non-specific and often
short-lasting response of the bone marrow to different diseases
such as malignancies or infections, is characterized by the
presence in the peripheral blood of immature red and white
cells. Methods: We present a case of leukoerythoblastosis
occurring in a 24 months old Mozambican girl, in the context of
a severe malaria episode and an associated urinary tract
infection. Peripheral blood smear was used for diagnosis of
malaria and leukoerythroblastosis. Enterobacter cloacae
isolation and antibiotic susceptibility testing were performed
by conventional microbiology. Results: Peripheral blood smear
was positive for Plasmodium falciparum and showed a
leukoerythroblastosis with red cell anisopoikilocytosis and left
shifted neutrophils. Urine culture confirmed the presence of a
multi-resistant E. cloacae. Treatment of underlying conditions
resolved the leukoerythroblastic reaction. Conclusions:
Leukoerythroblastosis may be related to different infectious
diseases and may also appear in the context of severe malaria.
Bacterial superinfection needs to be investigated.
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VARO, Rosauro, et al. Leukoerythroblastosis in a Young Child with Severe Malaria and
Superimposed Gram Negative Infection. Journal of Tropical Pediatrics. 2017. ISSN 0142-6338. [consulted: 9 of August of 2026]. Available at: https://hdl.handle.net/2445/119067