Low prevalence of Cfr-mediated linezolid resistance among methicillin-resistant Staphylococcus aureus in a Spanish hospital: case report on linezolid resistance acquired during linezolid therapy

dc.contributor.authorSierra, Josep M.
dc.contributor.authorCamoez, Mariana
dc.contributor.authorTubau, Fe
dc.contributor.authorGasch, Oriol
dc.contributor.authorPujol Rojo, Miquel
dc.contributor.authorMartín, Rogelio
dc.contributor.authorDomínguez Luzón, Ma. Ángeles (María Ángeles)
dc.date.accessioned2016-04-13T15:13:41Z
dc.date.available2016-04-13T15:13:41Z
dc.date.issued2013
dc.date.updated2016-04-13T15:13:46Z
dc.description.abstractLinezolid is an effective antimicrobial agent to treat methicillin-resistant Staphylococcus aureus (MRSA). Resistance to linezolid due to the cfr gene is described worldwide. The present study aimed to analyze the prevalence of the cfr-mediated linezolid resistance among MRSA clinical isolates in our area. A very low prevalence of cfr mediated linezolid resistance was found: only one bacteremic isolate out of 2 215 screened isolates. The only linezolid resistant isolate arose in a patient, previously colonized by MRSA, following linezolid therapy. Despite the low rate of resistance in our area, ongoing surveillance is advisable to avoid the spread of linezolid resistance.
dc.format.extent3 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec638652
dc.identifier.issn1932-6203
dc.identifier.pmid23554998
dc.identifier.urihttps://hdl.handle.net/2445/97365
dc.language.isoeng
dc.publisherPublic Library of Science (PLoS)
dc.relation.isformatofReproducció del document publicat a: http://dx.doi.org/10.1371/journal.pone.0059215
dc.relation.ispartofPLoS One, 2013, vol. 8, num. 3
dc.relation.urihttp://dx.doi.org/10.1371/journal.pone.0059215
dc.rightscc-by (c) Sierra, J.M. et al., 2013
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es
dc.sourceArticles publicats en revistes (Patologia i Terapèutica Experimental)
dc.subject.classificationStaphylococcus aureus
dc.subject.classificationUnitats de cures intensives
dc.subject.classificationInfeccions respiratòries
dc.subject.otherStaphylococcus aureus
dc.subject.otherIntensive care units
dc.subject.otherRespiratory infections
dc.titleLow prevalence of Cfr-mediated linezolid resistance among methicillin-resistant Staphylococcus aureus in a Spanish hospital: case report on linezolid resistance acquired during linezolid therapy
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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