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Article

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1985

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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/22429

Amyloid arthropathy in patients undergoing periodical haemodialysis for chronic renal failure: a new complication.

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http://dx.doi.org/10.1136/ard.44.11.729

Abstract

Seven patients (five male and two female) with chronic renal failure (CRF) treated by periodical haemodialysis presented with swelling and effusion of more than three months' duration in knees (four bilateral), shoulders (two, one of them bilateral), elbow (one), and ankle (one). Four had a carpal tunnel syndrome both clinically and electromyographically (three bilateral). All patients had hyperparathyroidism secondary to their CRF, which was not due to amyloidosis in any of them. The dialysis duration period varied from five to 14 years, with an average of 8.6 years. Amyloid deposits (Congo red positive areas with green birefringence under polarising microscopy) were shown in six of the seven synovial biopsy specimens of the knee, in five of the sediments of the synovial fluids, and in specimens removed during carpal tunnel syndrome surgery. No amyloid was found in the biopsy specimen of abdominal fat of six of the patients. The finding of amyloid only in the synovial membrane and fluid, and carpal tunnel, its absence in abdominal fat, and the lack of other manifestations of generalised amyloidosis (cardiomyopathy, malabsorption syndrome, macroglossia, etc.) and of Bence Jones myeloma (protein immunoelectrophoresis normal) raises the possibility that this is a form of amyloidosis which is peculiar to CRF treated by periodical haemodialysis.

Subject

Artropatia, Insuficiència renal crònica, Hemodiàlisi, Estudi de casos, Complicacions (Medicina)

Subject (English)

Arthropathy, Chronic renal failure, Hemodialysis, Case studies, Complications (Medicine)

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Articles publicats en revistes (Medicina)
Articles publicats en revistes (Fonaments Clínics)

Citation

MUÑOZ GÓMEZ, José, et al. Amyloid arthropathy in patients undergoing periodical haemodialysis for chronic renal failure: a new complication. Annals of the Rheumatic Diseases. 1985. Vol. 44, num. 11, pags. 729-733. ISSN 0003-4967. [consulted: 11 of June of 2026]. Available at: https://hdl.handle.net/2445/22429

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