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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/181486
The neural correlates of delay discounting in obesity and binge eating disorder
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Background and aims: Increased delay discounting is associated with obesity and binge eating disorder (BED). Although BED and obesity frequently co-occur, the neural mechanisms underlying delay discounting in these conditions remain poorly understood. Methods: Thirtyfive women with obesity, including 10 participants with obesity and BED and 31 controls completed a monetary delay discounting task during functional magnetic resonance imaging. Results: We identified that increased discounting rates were associated with decreased activity in the left anterior insula in participants with obesity compared to controls when choosing immediate rewards over delayed rewards (P-FWE < 0.05). An exploratory analysis comparing the BED subsample to the other groups did not detect significant differences. Discussion and conclusions: Our findings suggest decreased activity in the anterior insula may underlie heightened delay discounting in individuals with obesity, contributing the probability of choosing immediate rewards over delayed rewards based on emotional states. Future studies including larger, more diverse samples are required to confirm these effects.
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MIRANDA OLIVOS, Romina, STEWARD, Trevor, MARTÍNEZ ZALACAÍN, Ignacio, MESTRE BACH, Gemma, JUANEDA SEGUÍ, Asier, JIMÉNEZ-MURCIA, Susana, FERNÁNDEZ FORMOSO, José a., VILARRASA, Nuria, VECIANA DE LAS HERAS, Misericordia, CUSTAL, Nuria, VIRGILI, Nuria, LÓPEZ URDIALES, Rafael, MENCHÓN MAGRIÑÁ, José manuel, GRANERO, Roser, SORIANO MAS, Carles, FERNÁNDEZ ARANDA, Fernando. The neural correlates of delay discounting in obesity and binge eating disorder. _Journal of Behavioral Addictions_. 2021. Vol. 10, núm. 3, pàgs. 498–507. [consulta: 15 de gener de 2026]. ISSN: 2063-5303. [Disponible a: https://hdl.handle.net/2445/181486]