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Long-term clinical outcome of paraneoplastic cerebellar degeneration and anti-Yo antibodies

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The outcome of 34 women with anti-Yo-associated paraneoplastic cerebellar degeneration was reviewed. Three patients had not developed cancer after more than 4 years of follow-up. The only independent predictor for survival was the type of associated tumor (risk ratio, 1.79; 95% CI, 1.02 to 3.12). Median survival was 100 months for patients with breast cancer and 22 for those with gynecologic cancer. Although paraneoplastic cerebellar degeneration leads to the diagnosis of cancer in 63% of the patients, cancer progression was the cause of death in 52%.

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ROJAS-MARCOS, Iñigo, et al. Long-term clinical outcome of paraneoplastic cerebellar degeneration and anti-Yo antibodies. Neurology. 2000. Vol. 55, núm. 5, pàgs. 713-715. ISSN 0028-3878. [consulta: 8 de maig de 2026]. Disponible a: https://hdl.handle.net/2445/178218

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