Dialkylammonium tert-Butylmethylphosphinites: Stable Intermediates for the Synthesis of P-Stereogenic Ligands

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dc.contributor.authorSalomó i Prat, Ernest
dc.contributor.authorPrades, Amparo
dc.contributor.authorRiera i Escalé, Antoni
dc.contributor.authorVerdaguer i Espaulella, Xavier
dc.date.accessioned2017-07-25T08:38:28Z
dc.date.available2018-06-22T22:01:24Z
dc.date.issued2017-06-22
dc.date.updated2017-07-25T08:38:28Z
dc.description.abstractThe preparation of shelf-stable crystalline salts of tert-butylmethylphosphinous acid borane 1 is described. X-ray analysis of diisopropylammonium tert-butylmethylphosphinite borane 4 revealed the existence of a cyclic hydrogen-bond network in the solid state which accounts for the increased melting point and stability. Dialkylammonium phosphinite boranes are convenient precursors of the chiral tert-butylmethylphosphine fragment. Compound 4 can be directly employed in SN2@P reactions with different nucleophiles to yield valuable P-stereogenic intermediates and ligands.
dc.format.extent5 p.
dc.format.mimetypeapplication/pdf
dc.identifier.issn0022-3263
dc.identifier.pmid28640640
dc.identifier.urihttps://hdl.handle.net/2445/114291
dc.language.isoeng
dc.publisherAmerican Chemical Society
dc.relation.isformatofVersió postprint del document publicat a: https://doi.org/10.1021/acs.joc.7b01180
dc.relation.ispartofJournal of Organic Chemistry, 2017
dc.relation.urihttps://doi.org/10.1021/acs.joc.7b01180
dc.rights(c) American Chemical Society, 2017
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.sourceArticles publicats en revistes (Química Inorgànica i Orgànica)
dc.subject.classificationLligands (Bioquímica)
dc.subject.classificationCompostos fosforosos
dc.subject.classificationCatàlisi asimètrica
dc.subject.otherLigands (Biochemistry)
dc.subject.otherPhosphorus compounds
dc.subject.otherEnantioselective catalysis
dc.titleDialkylammonium tert-Butylmethylphosphinites: Stable Intermediates for the Synthesis of P-Stereogenic Ligands
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/acceptedVersion

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