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Endocrino Diabet Metabol - 2025 - Hassanpour Ardekanizadeh - Association Between Dietary Fatty Acid Intake With.pdf (272.87 KB)

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2025-12-21

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cc-by (c) Ardekanizadeh, Naeemeh Hassanpour et al., 2025
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/228751

Association Between Dietary Fatty Acid Intake With Cardiovascular Disease Risk and Serum Lipid Levels

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https://doi.org/10.1002/edm2.70148

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Background Despite early interest in the effects of dietary fats on cardiovascular diseases (CVDs), substantial controversy remains regarding the evidence linking different types of fatty acids to CVDs. This study aimed to examine the association between dietary fat intake, CVD risk, and serum lipid biomarkers.Methods This cross-sectional study included data from 4200 adult participants (1218 patients with CVDs and 2982 healthy participants) from the Persian Cohort Study. Data on heart disease (hypertension, myocardial infarction, and ischemic heart disease) were collected. Dietary intake was assessed using a validated food frequency questionnaire (FFQ), and the intake of different fatty acids was evaluated using Nutritionist-IV software. Serum lipid profiles were analysed using enzymatic and chromatographic methods.Results Higher monounsaturated fatty acids (MUFA) intake showed an inverse association with CVDs (OR = 0.931, 95% CI: 0.867-0.998, p = 0.045). Adjustments for age, gender, smoking, alcohol consumption, physical activity, BMI, and caloric intake did not alter this association. No significant associations were observed for other dietary fats.Conclusion The findings suggest an inverse association between MUFA intake and CVD risk. Further longitudinal studies are warranted to confirm these results.

Matèries

Àcids grassos en la nutrició, Trastorns del metabolisme dels lípids, Malalties cardiovasculars

Matèries (anglès)

Fatty acids in human nutrition, Lipid metabolism disorders, Cardiovascular diseases

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Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

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ARDEKANIZADEH, Naeemeh Hassanpour, et al. Association Between Dietary Fatty Acid Intake With Cardiovascular Disease Risk and Serum Lipid Levels. Endocrinology Diabetes & Metabolism. 2026. Vol. 9, num. 1, pags. e70148. ISSN 2399-9780. [consulted: 20 of July of 2026]. Available at: https://hdl.handle.net/2445/228751

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