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cc-by (c) Testa, Giulia et al., 2022
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/192498

Impact of impulsivity and therapy response in eating disorders from a neurophysiological, personality and cognitive perspective

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Impulsivity, as a multidimensional construct, has been linked to eating disorders (EDs) and may negatively impact treatment response. The study aimed to identify the dimensions of impulsivity predicting poor remission of ED symptoms. A total of 37 ED patients underwent a baseline assessment of impulsive personality traits and inhibitory control, including the Stroop task and the emotional go/no-go task with event-related potentials (ERPs) analysis. The remission of EDs symptomatology was evaluated after 3 months of cognitive-behavioral therapy (CBT) and at a 2-year follow-up. Poor remission after CBT was predicted by poor inhibitory control, as measured by the Stroop task. At 2 years, the risk of poor remission was higher in patients with higher novelty seeking, lower inhibitory control in the Stroop and in ERPs indices (N2 amplitudes) during the emotional go/no-go task. The present results highlight inhibitory control negatively impacting both short- and long-term symptomatology remission in ED patients. On the other hand, high novelty seeking and ERPs indices of poor inhibition seem to be more specifically related to long-term remission. Therefore, a comprehensive assessment of the impulsivity dimension in patients with ED is recommended to tailor treatments and improve their efficacy.

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TESTA, Giulia, et al. Impact of impulsivity and therapy response in eating disorders from a neurophysiological, personality and cognitive perspective. Nutrients. 2022. Vol. 14, num. 23. ISSN 2072-6643. [consulted: 8 of August of 2026]. Available at: https://hdl.handle.net/2445/192498

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