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2024-09-01

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cc by (c) Paz Graniel, Indira et al., 2024
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/219672

Long-term association between water intake and kidney function in a population at high cardiovascular risk

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https://doi.org/10.1016/j.jnha.2024.100327

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Objectives: The evidence on water intake in the prevention of kidney function decline is scarce at population level in well-being individuals at high cardiovascular risk. Therefore, we aimed to longitudinally evaluate the associations between total water intake and subtypes and kidney function, through estimated-Glomerular Filtration Rate (eGFR). Methods: Three-year prospective analysis conducted in 1986 older adults (aged 55-75 year) with overweight/obesity and metabolic syndrome from the PREDIMED-Plus study. Water intake was assessed using validated beverage and food frequency questionnaires. Serum creatinine-based eGFR (SCr-based eGFR; ml/min/1.73 m2) was estimated using the CKD-EPI equation at baseline, one-year and 3-years of follow-up. Mixed-effects linear regression models were fitted to evaluate the associations between baseline total water intake and subtypes, and SCr-based eGFR over 3-years of follow-up. Results: Participants in the highest baseline tertile of total water intake, plain water and water from all fluids showed a lower decrease in SCr-based eGFR after 3-years of follow-up, compared to those in the lowest tertile. Participants with the highest tap water consumption showed a lower SCr-based eGFR decline after 1-year and 3-years of follow-up, in comparerd to participants in the lowest intake category (T3 vs. T1: β: 1.4 ml/min/1.73 m2; 95%CI: 0.5-2.3, β: 1.0; 95%CI: 0.1-2.0, respectively). Conclusions: Plain water rather than other water sources, and especially tap water, was associated with lower kidney function decline assessed through eGFR over 3-years of follow-up, in older individuals at high cardiovascular risk.

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Metabolisme, Malalties cardiovasculars, Ronyó

Matèries (anglès)

Metabolism, Cardiovascular diseases, Kidney

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Articles publicats en revistes (Ciències Clíniques)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

Citació

PAZ GRANIEL, Indira, VALLE-HITA, Cristina, BABIO, Nancy, SERRA MAJEM, Lluís, VIOQUE, Jesús, ZOMEÑO, María dolores, CORELLA PIQUER, Dolores, PINTÓ SALA, Xavier, CANO-IBAÑEZ, Naomi, TUR MARÍ, Josep a. (josep antoni), CUADRADO-SOTO, Esther, MARTÍNEZ, J. alfredo, TORRES-COLLADO, Laura, GODAY ARNÓ, Albert, FERNÁNDEZ-CARRIÓN, Rebeca, NISSENSHON, Mariela, RIERA MESTRE, Antoni, GARRIDO-GARRIDO, Eva, BOUZAS, Cristina, ABETE, Itziar, DAIMIEL, Lidia, CORNEJO-PAREJA, Isabel, VÁZQUEZ RUIZ, Zenaida, KHOURY, Nadine, PÉREZ VEGA, Karla alejandra, SALAS SALVADÓ, Jordi, DÍAZ-LÓPEZ, Andrés. Long-term association between water intake and kidney function in a population at high cardiovascular risk. _Journal of Nutrition_. Health & Aging. Vol.  2024, núm. 28, pàgs. 9. [consulta: 15 de gener de 2026]. ISSN: 1279-7707. [Disponible a: https://hdl.handle.net/2445/219672]

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