Miniatura

Fitxers

262340.pdf (848.72 KB)

Tipus de document

Article

Versió

Versió publicada

Data de publicació

2023-04-07

Llicència de publicació

cc-by (c) Baeza, Inmaculada, 1970- et al., 2023
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/220733

Prodromal symptoms and the duration of untreated psychosis in first episode of psychosis patients: what differences are there between early vs. adult onset and between schizophrenia vs. bipolar disorder?

Títol de la revista

Autors

Director/Tutor

ISSN de la revista

Títol del volum

Recurs relacionat

https://doi.org/10.1007/s00787-023-02196-7

Resum

To assess the role of age (early onset psychosis-EOP < 18 years vs. adult onset psychosis-AOP) and diagnosis (schizophrenia spectrum disorders-SSD vs. bipolar disorders-BD) on the duration of untreated psychosis (DUP) and prodromal symptoms in a sample of patients with a first episode of psychosis. 331 patients with a first episode of psychosis (7-35 years old) were recruited and 174 (52.6%) diagnosed with SSD or BD at one-year follow-up through a multicenter longitudinal study. The Symptom Onset in Schizophrenia (SOS) inventory, the Positive and Negative Syndrome Scale and the structured clinical interviews for DSM-IV diagnoses were administered. Generalized linear models compared the main effects and group interaction. 273 AOP (25.2 ± 5.1 years; 66.5% male) and 58 EOP patients (15.5 ± 1.8 years; 70.7% male) were included. EOP patients had significantly more prodromal symptoms with a higher frequency of trouble with thinking, avolition and hallucinations than AOP patients, and significantly different median DUP (91 [33-177] vs. 58 [21-140] days; Z = - 2.006, p = 0.045). This was also significantly longer in SSD vs. BD patients (90 [31-155] vs. 30 [7-66] days; Z = - 2.916, p = 0.004) who, moreover had different profiles of prodromal symptoms. When assessing the interaction between age at onset (EOP/AOP) and type of diagnosis (SSD/BD), avolition was significantly higher (Wald statistic = 3.945; p = 0.047), in AOP patients with SSD compared to AOP BD patients (p = 0.004). Awareness of differences in length of DUP and prodromal symptoms in EOP vs. AOP and SSD vs. BD patients could help improve the early detection of psychosis among minors.

Matèries

Edat, Diagnòstic, Trastorn bipolar, Psicosi, Símptomes, Esquizofrènia

Matèries (anglès)

Age, Diagnosis, Manic-depressive illness, Psychoses, Symptoms, Schizophrenia

Citació

Col·leccions

Articles publicats en revistes (Medicina)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

Citació

BAEZA, Inmaculada, SERNA GÓMEZ, Elena de la, MEZQUIDA MATEOS, Gisela, CUESTA, Manuel j., VIETA I PASCUAL, Eduard, AMORETTI GUADALL, Silvia, LOBO, Antonio, GONZÁLEZ-PINTO, Ana, DÍAZ CANEJA, Covadonga m., CORRIPIO, Iluminada, VALLI, Isabel, PUIG NAVARRO, Olga, MANÉ SANTACANA, Anna, BIOQUE ALCÁZAR, Miquel, AYORA, Miriam, BERNARDO ARROYO, Miquel, CASTRO FORNIELES, Josefina, the PEPs group. Prodromal symptoms and the duration of untreated psychosis in first episode of psychosis patients: what differences are there between early vs. adult onset and between schizophrenia vs. bipolar disorder?. _European Child & Adolescent Psychiatry_. 2023. Vol. 33, núm. 3, pàgs. 799-810. [consulta: 10 de gener de 2026]. ISSN: 1018-8827. [Disponible a: https://hdl.handle.net/2445/220733]

Exportar metadades

JSON - METS

Compartir registre