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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/171791
Prevalence of Sjogren's syndrome in the general adult population in Spain: estimating the proportion of undiagnosed cases
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To estimate the prevalence of Sjogren's syndrome (SS) in the adult Spanish population we performed a population-based multicenter cross-sectional study. Cases were defined by the American-European Consensus Group criteria proposed in 2002. A total of 4,916 subjects aged 20 years or over were included. The estimated prevalence of SS (including primary and secondary forms) in the adult population in Spain was 0.33% (95% CI 0.21-0.53). Extrapolating to the total population of the country aged >= 20 years (around 37.7 million persons), there would be around 125,000 cases of SS in Spain. Considering only primary SS, the estimated prevalence was 0.25% (95% CI 0.15-0.43) or 1 person in 400. The prevalence of primary SS in Spain is comparable to that reported in other European studies with a similar design and diagnostic criteria. Based on these results, primary SS could not be considered a rare (orphan) disease. Only 50% of cases had already been diagnosed with SS prior EPISER 2016 study, confirming the existence of a non-negligible proportion of undiagnosed cases in the general population.
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NARVÁEZ, Javier, SÁNCHEZ FERNÁNDEZ, Simón ángel, SEOANE MATO, Daniel, DÍAZ GONZÁLEZ, Federico, BUSTABAD, Sagrario. Prevalence of Sjogren's syndrome in the general adult population in Spain: estimating the proportion of undiagnosed cases. _Scientific Reports_. 2020. Vol. 10. [consulta: 31 de gener de 2026]. [Disponible a: https://hdl.handle.net/2445/171791]