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2019-01

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cc-by (c) Arioli, Federica et al., 2019
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/174410

A Straightforward Synthesis of Functionalized cis-Perhydroisoquinolin-1-ones

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https://doi.org/10.3390/molecules24030557

Abstract

Base-catalyzed annulation reactions of 5,6-dihydro-2(1H)-pyridones with Nazarov-type reagents are reported. The effect of the solvent polarity and the concentration of the reagents is studied. The process involves two successive Michael additions and stereoselectively provides functionalized cis-perhydroisoquinolin-1-ones.

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Indicadors (Química), Proves i reactius químics, Lactames, Química orgànica

Subject (English)

Indicators and test-papers, Chemical tests and reagents, Lactams, Organic chemistry

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Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)
Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)

Citation

ARIOLI, Federica, et al. A Straightforward Synthesis of Functionalized cis-Perhydroisoquinolin-1-ones. Molecules. 2019. Vol. 24, num. 557-570. ISSN 1420-3049. [consulted: 18 of June of 2026]. Available at: https://hdl.handle.net/2445/174410

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