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journal.pone.0275615 (1).pdf (460.15 KB)

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2022-10-10

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cc by (c) Aranda, Judit et al., 2022
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/196110

Persistent COVID-19 symptoms 1 year after hospital discharge: A prospective multicenter study

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https://doi.org/10.1371/journal.pone.0275615

Abstract

Objective To determine the health status and exercise capacity of COVID-19 survivors one year after hospital discharge. Methods This multicenter prospective study included COVID-19 survivors 12 months after hospital discharge. Participants were randomly selected from a large cohort of COVID-19 patients who had been hospitalized until 15th April 2020. They were interviewed about persistent symptoms, underwent a physical examination, chest X-ray, and a 6-minute walk test (6MWT). A multivariate analysis was performed to determine the risk factors for persistent dyspnea. Results Of the 150 patients included, 58% were male and the median age was 63 (IQR 54-72) years. About 82% reported >= 1 symptoms and 45% had not recovered their physical health. The multivariate regression analysis revealed that the female sex, chronic obstructive pulmonary disease, and smoking were independent risk factors for persistent dyspnea. Approximately 50% completed less than 80% of the theoretical distance on the 6MWT. Only 14% had an abnormal X-ray, showing mainly interstitial infiltrates. A third of them had been followed up in outpatient clinics and 6% had undergone physical rehabilitation. Conclusion Despite the high rate of survivors of the first wave of the COVID-19 pandemic with persistent symptomatology at 12 months, the follow-up and rehabilitation of these patients has been really poor. Studies focusing on the role of smoking in the persistence of COVID-19 symptoms are lacking.

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Pandèmia de COVID-19, 2020-, Epidemiologia, Símptomes, Rehabilitació mèdica

Subject (English)

COVID-19 Pandemic, 2020-, Epidemiology, Symptoms, Medical rehabilitation

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Articles publicats en revistes (Ciències Clíniques)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

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ARANDA LOBO, Judit, et al. Persistent COVID-19 symptoms 1 year after hospital discharge: A prospective multicenter study. PLOS ONE. 2022. Vol. 17, num. 10, pags. e0275615. ISSN 1932-6203. [consulted: 9 of June of 2026]. Available at: https://hdl.handle.net/2445/196110

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