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2017-08-04

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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/167518

Enantioselective Synthesis of Spiro[indolizidine-1,3 '-oxindoles]

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https://doi.org/10.1021/acs.orglett.71301818

Abstract

A three-step procedure for the enantioselective synthesis of spiro[indolizidine-1,3'-oxindoles], consisting of a stereoselective cyclocondensation reaction between (S)-tryptophanol and a prochiral or racemic 5-oxoester, bromination of the resulting oxazolopiperidone lactam, and a final stereoselective spirocyclization, is reported.

Subject

Síntesi orgànica, Enantiòmers, Oxidació, Compostos heterocíclics

Subject (English)

Organic synthesis, Enantiomers, Oxidation, Heterocyclic compounds

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Articles publicats en revistes (Nutrició, Ciències de l'Alimentació i Gastronomia)
Articles publicats en revistes (Institut de Biomedicina (IBUB))

Citation

PÉREZ BOSCH, Maria, et al. Enantioselective Synthesis of Spiro[indolizidine-1,3 '-oxindoles]. Organic Letters. 2017. Vol. 19, num. 15, pags. 4050-4053. ISSN 1523-7060. [consulted: 12 of June of 2026]. Available at: https://hdl.handle.net/2445/167518

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