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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/194952
Azithromycin to Prevent Pertussis in Household Contacts, Catalonia and Navarre, Spain, 2012-2013
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We retrospectively assessed the effectiveness of azithromycin in preventing transmission of pertussis to a patient's household contacts. We also considered the duration between symptom onset in the primary patient and azithromycin administration. We categorized contacts into 4 groups: those treated within <7 days, 8-14 days, 15-21 days, and >21 days after illness onset in the primary patient. We studied 476 primary index patients and their 1,975 household contacts, of whom 4.5% were later identified as having pertussis. When contacts started chemoprophylaxis within <21 days after the primary patient's symptom onset, the treatment was 43.9% effective. Chemoprophylaxis started >14 days after primary patient's symptom onset was less effective. We recommend that contacts of persons with pertussis begin chemoprophylaxis within <14 days after primary patient's symptom onset.
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ÁLVAREZ, Josep, GODOY I GARCÍA, Pere, PLANS RUBIO, Pedro, CAMPS, Neus, CAROL, Mónica, CARMONA I PARCERISA, Glòria, SOLANO, Rubén, RIUS, Cristina, MINGUELL, Sofía, BARRABEIG I FABREGAT, Irene, SALA FARRÉ, Maria rosa, RODRÍGUEZ, Raquel, GARCIA CENOZ, Manuel, MUÑOZ ALMAGRO, Carmen, DOMÍNGUEZ GARCÍA, Àngela, Transmission of Pertussis in Households Working Group. Azithromycin to Prevent Pertussis in Household Contacts, Catalonia and Navarre, Spain, 2012-2013. _Emerging Infectious Diseases_. 2020. Vol. 26, núm. 11, pàgs. 2678-2684. [consulta: 25 de gener de 2026]. ISSN: 1080-6040. [Disponible a: https://hdl.handle.net/2445/194952]