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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/108384
Asymmetric intermolecular cobalt-catalyzed Pauson-Khand reaction using a p-stereogenic bis-phosphane
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The asymmetric intermolecular and catalytic Pauson-Khand reaction has remained an elusive goal since Khand and Pauson discovered this transformation. Using a novel family of P-stereogenic phosphanes, we developed the first catalytic system with useful levels of enantioselection for the reaction of norbornadiene and trimethylsilylacetylene. The results demonstrate that Co-bisphosphane systems are sufficiently reactive and that they lead to high selectivity in the intermolecular process.
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ORGUÉ GASSOL, Sílvia, et al. Asymmetric intermolecular cobalt-catalyzed Pauson-Khand reaction using a p-stereogenic bis-phosphane. Organic Letters. 2014. Vol. 17, num. 250-253. ISSN 1523-7060. [consulted: 6 of October of 2026]. Available at: https://hdl.handle.net/2445/108384