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1-s2.0-S0211699524001231-main.pdf (1.22 MB)

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2024-12-20

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cc by-nc-nd (c) Bermejo, Sheila et al, 2025
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/222096

A predictive model of non-diabetic kidney disease in patients with diabetes mellitus and chronic kidney disease. A Spanish multi-center study

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Recurs relacionat

https://doi.org/10.1016/j.nefro.2024.12.007

Resum

Aims: Kidney biopsy is increasing in patients with diabetes and around 50-60% of patients with diabetes have non-diabetic kidney disease (NDKD). Identifying NDKD is crucial since these patients have a better renal prognosis and survival compared to patients with diabetic nephropathy (DN). The objective of this study is to provide a clinical practice tool for through a predictive model of NDKD. Material and methods: Observational and multicenter Spanish study of the pathological results of kidney biopsies in patients with diabetes from 2002 to 2014. A logistic regression analysis and the probability of presenting NDKD was calculated using a punctuation score. Results: A total of 832 patients with diabetes and renal biopsy were analyzed. An accurate risk-predictive model for NDKD was developed with five top-ranked non-invasive clinical variables (age, serum creatinine, presence of diabetic retinopathy, microhematuria and peripheral vascular disease) obtaining a score for each one allowing for a proper prediction of NDKD. Conclusions: In our study, we developed a risk-stratification score to calculate the probability of NDKD. This could be in a next future a useful tool for the clinical indication of renal biopsy in patients with diabetes and kidney disease. (c) 2024 Published by Elsevier Espana, S.L.U. on behalf of Sociedad Espanola de Nefrolog & imath;a. This is an open access article under the CC BY-NC-ND license (http://creativecommons. org/licenses/by-nc-nd/4.0/).

Matèries

Diabetis, Malalties del ronyó

Matèries (anglès)

Diabetes, Kidney diseases

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Col·leccions

Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

Citació

BERMEJO, Sheila, et al. A predictive model of non-diabetic kidney disease in patients with diabetes mellitus and chronic kidney disease. A Spanish multi-center study. Nefrología. 2024. Vol. 45, num. 5, pags. 360-368. ISSN 1989-2284. [consulted: 18 of August of 2026]. Available at: https://hdl.handle.net/2445/222096

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