Cyclocondensation reactions of 2-acyl-3-indoleacetic acid derivatives with phenylglycinol. Enantioselective synthesis of 1-substituted tetrahydro-b-carboline alkaloids

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dc.contributor.authorAmat Tusón, Mercedes
dc.contributor.authorSubrizi, Fabiana
dc.contributor.authorElias, Viviane
dc.contributor.authorLlor Brunés, Núria
dc.contributor.authorMolins, Elies
dc.contributor.authorBosch Cartes, Joan
dc.date.accessioned2020-06-04T07:42:42Z
dc.date.available2020-06-04T07:42:42Z
dc.date.issued2012-03
dc.date.updated2020-06-04T07:42:42Z
dc.description.abstractCyclocondensation reactions between a variety of 2‐acyl‐3‐indoleacetic acid derivatives and (R )‐phenylglycinol were studied. Successful results were obtained from N ‐alkyl keto acid derivatives. The resulting tetracyclic lactams provide straightforward access to enantiopure 1‐substituted tetrahydro‐β‐carboline alkaloids.
dc.format.extent8 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec603301
dc.identifier.issn1434-193X
dc.identifier.urihttps://hdl.handle.net/2445/164192
dc.language.isoeng
dc.publisherWiley-VCH
dc.relation.isformatofVersió postprint del document publicat a: https://doi.org/10.1002/ejoc.201101718
dc.relation.ispartofEuropean Journal of Organic Chemistry, 2012, vol. 2012, num. 9, p. 1835-1842
dc.relation.urihttps://doi.org/10.1002/ejoc.201101718
dc.rights(c) Wiley-VCH, 2012
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.sourceArticles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
dc.subject.classificationSíntesi asimètrica
dc.subject.classificationAlcaloides
dc.subject.classificationLactames
dc.subject.otherAsymmetric synthesis
dc.subject.otherAlkaloids
dc.subject.otherLactams
dc.titleCyclocondensation reactions of 2-acyl-3-indoleacetic acid derivatives with phenylglycinol. Enantioselective synthesis of 1-substituted tetrahydro-b-carboline alkaloids
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/acceptedVersion

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