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cc by (c) Luca, Giuseppe de et al, 2022
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/191842

Impact of Smoking Status on Mortality in STEMI Patients Undergoing Mechanical Reperfusion for STEMI: Insights from the ISACS–STEMI COVID-19 Registry

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The so-called smoking paradox, conditioning lower mortality in smokers among STEMI patients, has seldom been addressed in the settings of modern primary PCI protocols. The ISACS-STEMI COVID-19 is a large-scale retrospective multicenter registry addressing in-hospital mortality, reperfusion, and 30-day mortality among primary PCI patients in the era of the COVID-19 pandemic. Among the 16,083 STEMI patients, 6819 (42.3%) patients were active smokers, 2099 (13.1%) previous smokers, and 7165 (44.6%) non-smokers. Despite the impaired preprocedural recanalization (p < 0.001), active smokers had a significantly better postprocedural TIMI flow compared with non-smokers (p < 0.001); this was confirmed after adjustment for all baseline and procedural confounders, and the propensity score. Active smokers had a significantly lower in-hospital (p < 0.001) and 30-day (p < 0.001) mortality compared with non-smokers and previous smokers; this was confirmed after adjustment for all baseline and procedural confounders, and the propensity score. In conclusion, in our population, active smoking was significantly associated with improved epicardial recanalization and lower in-hospital and 30-day mortality compared with previous and non-smoking history.

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LUCA, Giuseppe de, ALGOWHARY, Magdy, UGUZ, Berat, OLIVEIRA, Dinaldo c., GANYUKOV, Vladimir, ZIMBAKOV, Zan, CERCEK, Miha, JENSEN, Lisette okkels, LOH, Poay huan, CALMAC, Lucian, FERRER, Gerard roura i., QUADROS, Alexandre, MILEWSKI, Marek, SCOTTO D’UCCIO, Fortunato, BIRGELEN, Clemens von, VERSACI, Francesco, TEN BERG, Jurrien, CASELLA, Gianni, WONG SUNG LUNG, Aaron, KALA, Petr, DÍEZ GIL, José luis, CARRILLO, Xavier, DIRKSEN, Maurits, BECERRA  MUÑOZ, Victor m., LEE, Michael kang-yin, JUZAR, Dafsah arifa, JOAQUIM, Rodrigo de moura, PALADINO, Roberto, MILICIC, Davor, DAVLOUROS, Periklis, BAKRACESKI, Nikola, ZILIO, Filippo, DONAZZAN, Luca, KRAAIJEVELD, Adriaan, GALASSO, Gennaro, ARPAD, Lux, LUCIA, Marinucci, VINCENZO, Guiducci, MENICHELLI, Maurizio, SCOCCIA, Alessandra, YAMAC, Aylin hatice, UGUR MERT, Kadir, FLORES RIOS, Xacobe, KOVARNIK, Tomas, KIDAWA, Michal, MOREU, Josè, VINCENT, Flavien, FABRIS, Enrico, MARTÍNEZ LUENGAS, Iñigo lozano, BOCCALATTE, Marco, BOSA OJEDA, Francisco, ARELLANO SERRANO, Carlos, CAIAZZO, Gianluca, CIRRINCIONE, Giuseppe, KAO, Hsien-li, SANCHIS FORÉS, Juan, VIGNALI, Luigi, PEREIRA, Helder, MANZO, Stephane, ORDOÑEZ, Santiago, ÖZKAN, Alev arat, SCHELLER, Bruno, LEHTOLA, Heidi, TELES, Rui, MANTIS, Christos, ANTTI, Ylitalo, BRUM SILVEIRA, João antónio, ZONI, Rodrigo, BESSONOV, Ivan, SAVONITTO, Stefano, KOCHIADAKIS, George, ALEXOPULOS, Dimitrios, URIBE, Carlos e., KANAKAKIS, John, FAURIE, Benjamin, GABRIELLI, Gabriele, GUTIERREZ BARRIOS, Alejandro, BACHINI, Juan pablo, ROCHA, Alex, TAM, Frankie chor-cheung, RODRIGUEZ, Alfredo, LUKITO, Antonia anna, SAINT-JOY, Veauthyelau, PESSAH, Gustavo, TUCCILLO, Andrea, CORTESE, Giuliana, PARODI, Guido, BOURAGHDA, Mohamed abed, KEDHI, Elvin, LAMELAS, Pablo, SURYAPRANATA, Harry, NARDIN, Matteo, VERDOIA, Monica. Impact of Smoking Status on Mortality in STEMI Patients Undergoing Mechanical Reperfusion for STEMI: Insights from the ISACS–STEMI COVID-19 Registry. _Journal of Clinical Medicine_. 2022. Vol. 11, núm. 22. [consulta: 24 de gener de 2026]. ISSN: 2077-0383. [Disponible a: https://hdl.handle.net/2445/191842]

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