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Viscerotropic disease: case definition and guidelines for collection, analysis, and presentation of immunization safety data
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Viscerotropic disease (VTD) is defined as acute multiple organ system dysfunction that occurs following vaccination. The severity of VTD ranges from relatively mild multisystem disease to severe multiple organ system failure and death. The term VTD was first used shortly after the initial published reports in 2001 of febrile multiple organ system failure following yellow fever (YF) vaccination. To date, VTD has been reported only in association with YF vaccine and has been thus referred to as YF vaccine-associated viscerotropic disease (YEL-AVD).
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GERSHMAN, Mark d., STAPLES, J.erin, BENTSI-ENCHILL, Adwoa d., BREUGELMANS, J.gabrielle, BRITO, Glacus s., BASTOS CAMACHO, Luiz a., COTTIN, Pascale, DOMINGO, Cristina, DURBIN, Anna, GASCON, Joaquim, GUENANECHE, Fouzia, HAYES, Edward b., JELENIK, Zsuzsanna, KHROMAVA, Alena, MENEZES MARTINS, Reinaldo de, MASANA WILSON, Mario, MASSY, Nathalie, NASIDI, Abdulsalami, NIEDRIG, Matthias, SHERWAT, Adam, TSAI, Theodore, VILELLA I MORATÓ, Anna, WILSON, Mary elisabeth, KOHL, Katrin s., The Brighton Collaboration Viscerotropic Disease Working Group. Viscerotropic disease: case definition and guidelines for collection, analysis, and presentation of immunization safety data. _Vaccine_. 2012. Vol. 30, núm. 33, pàgs. 5038-5058. [consulta: 22 de gener de 2026]. ISSN: 0264-410X. [Disponible a: https://hdl.handle.net/2445/148049]