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cc by (c) Sáez-López et al., 2016
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/101551

Characterization of Vaginal Escherichia coli Isolated from Pregnant Women in Two Different African Sites

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The relevance of vaginal colonization of pregnant women by Escherichia coli is poorly understood, despite these strains sharing a similar virulence profile with other extraintestinal pathogenic E. coli producing severe obstetric and neonatal infections. We characterized the epidemiology, antimicrobial susceptibility and virulence profiles of 84 vaginal E. coli isolates from pregnant women from Rabat (Morocco) and Manhica (Mozambique), two very distinct epidemiological settings. Low levels of antimicrobial resistance were observed to all drugs tested, except for trimethoprim-sulfamethoxazole in Manhica, where this drug is extensively used as prophylaxis for opportunistic HIV infections. The most prevalent virulence factors were related to iron acquisition systems. Phylogroup A was the most common in Rabat, while phylogroups E and non-typeable were the most frequent in Manhica. Regardless of the apparently "low virulence" of these isolates, the frequency of infections is higher and the outcomes more devastating in constrained-resources conditions, especially among pregnant women and newborns.

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SÁEZ-LÓPEZ, Emma, COSSA, Anelsio, BENMESSAOUD, Rachid, MADRID, Lola, MORALEDA REDECILLA, Cinta, VILLANUEVA, Sonia, TLIGUI, Houssain, MOIANE, Benilde, ALAMI, Hassan, MASSORA, Sérgio, BEZAD, Rachid, MANDOMANDO, Inácio, BOSCH MESTRES, Jordi, VILA ESTAPÉ, Jordi, BASSAT ORELLANA, Quique, SOTO GONZÁLEZ, Sara m.. Characterization of Vaginal Escherichia coli Isolated from
                Pregnant Women in Two Different African Sites. _PLoS One_. 2016. Vol. 11, núm. 7, pàgs. e0158695. [consulta: 25 de febrer de 2026]. ISSN: 1932-6203. [Disponible a: https://hdl.handle.net/2445/101551]

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