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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/174212
Alcohol Consumption and Risk of Parkinson's Disease: Data from a Large Prospective European Cohort
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Background: Parkinson's disease (PD) etiology is not well understood. Reported inverse associations with smoking and coffee consumption prompted the investigation of alcohol consumption as a risk factor, for which evidence is inconclusive. Objective: To assess the associations between alcohol consumption and PD risk. Methods: Within NeuroEPIC4PD, a prospective European population-based cohort, 694 incident PD cases were ascertained from 209,998 PD-free participants. Average alcohol consumption at different time points was self-reported at recruitment. Cox regression hazard ratios were estimated for alcohol consumption and PD occurrence. Results: No associations between baseline or lifetime total alcohol consumption and PD risk were observed. Men with moderate lifetime consumption (5-29.9 g/day) were at ~50% higher risk compared with light consumption (0.1-4.9 g/day), but no linear exposure-response trend was observed. Analyses by beverage type also revealed no associations with PD. Conclusion: Our data reinforce previous findings from prospective studies showing no association between alcohol consumption and PD risk. © 2020 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society.
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PETERS, Susan, et al. Alcohol Consumption and Risk of Parkinson's Disease: Data from a Large Prospective European Cohort. Movement Disorders. 2020. Vol. 35, num. 7, pags. 1258-1263. [consulted: 13 of August of 2026]. Available at: https://hdl.handle.net/2445/174212