Miniatura

Fitxers

238172.pdf (573.18 KB)

Tipus de document

Article

Versió

Versió acceptada

Data de publicació

2021-09-07

Tots els drets reservats

Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/227347

Characteristics and outcome of acute heart failure in infective endocarditis: focus on cardiogenic shock.

Títol de la revista

Autors

Director/Tutor

ISSN de la revista

Títol del volum

Recurs relacionat

https://doi.org/10.1093/cid/ciab098

Resum

Background: Studies investigating the impact of cardiogenic shock (CS) on endocarditis are lacking. Methods: Prospectively collected cohort from 35 Spanish centers (2008-2018). Logistic regression analyses were performed to identify risk factors for developing CS and predictors of mortality. Results: Among 4856 endocarditis patients, 1652 (34%) had acute heart failure (AHF) and 244 (5%) CS. Compared with patients without AHF and AHF but no CS, patients with CS presented higher rates of surgery (40.5%, 52.5%, and 68%; P < .001) and in-hospital mortality (16.3%, 39.1%, and 52.5%). Compared with patients with septic shock, CS patients presented higher rates of surgery (42.5% vs 68%; P < .001) and lower rates of in-hospital and 1-year mortality (62.3% vs 52.5%, P = .008, and 65.3% vs 57.4%, P = .030). Severe aortic and mitral regurgitation (OR [95% CI], 2.47 [1.82-3.35] and 3.03 [2.26-4.07]; both P < .001), left-ventricle ejection fraction <60% (1.72; 1.22-2.40; P = .002), heart block (2.22; 1.41-3.47; P = .001), tachyarrhythmias (5.07; 3.13-8.19; P < .001), and acute kidney failure (2.29; 1.73-3.03; P < .001) were associated with higher likelihood of developing CS. Prosthetic endocarditis (2.03; 1.06 -3.88; P = .032), Staphylococcus aureus (3.10; 1.16 -8.30; P = .024), tachyarrhythmias (3.09; 1.50-10.13; P = .005), and not performing cardiac surgery (11.40; 4.83-26.90; P < .001) were associated with a higher risk of mortality. Conclusions: AHF is common among patients with endocarditis. CS is associated with high mortality and should be promptly identified and assessed for cardiac surgery. Trial registration: ClinicalTrials.gov NCT00871104.

Matèries

Aturada cardíaca, Cirurgia, Endocarditis

Matèries (anglès)

Cardiac arrest, Surgery, Endocarditis

Citació

Col·leccions

Articles publicats en revistes (Medicina)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

Citació

PERICÀS, Juan m., HERNÁNDEZ MENESES, Marta, MUÑOZ, Patricia, MARTÍNEZ SELLÉS, Manuel, ÁLVAREZ URIA, Ana, ALARCÓN, Aristides de, GUTIÉRREZ CARRETERO, Encarnación, GOENAGA SÁNCHEZ, Miguel ángel, ZARAUZA NAVARRO, Manuel jesús, FALCES SALVADOR, Carles, RODRÍGUEZ ESTEBAN, María ángeles, HIDALGO TENORIO, Carmen, HERNÁNDEZ CABRERA, Michele, MIRÓ MEDA, José m., Spanish Collaboration on Endocarditis—Grupo de Apoyo al Manejo de la Endocarditis Infecciosa en España (GAMES). Characteristics and outcome of acute heart failure in infective endocarditis: focus on cardiogenic shock.. _Clinical Infectious Diseases_. 2021. Vol. 73, núm. 5, pàgs. 765-774. [consulta: 3 de març de 2026]. ISSN: 1058-4838. [Disponible a: https://hdl.handle.net/2445/227347]

Exportar metadades

JSON - METS

Compartir registre