Files
Document type
ArticleVersion
Published versionPublication date
Publication license
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/53783
Effect of cafeteria diet feeding on soleus intramyocellular lipid of Wistar rats
Journal Title
Director/Tutor
Journal ISSN
Volume Title
Related resource
Abstract
Background: The presence of lipid besides muscle fibres facilitates the energy supply for exercise, but it is also indicative of insulin resistance in the untrained. Muscle lipid is associated with increased dietary energy: hyperlipidic diets induce an increase in intramyocellular lipid deposition in skeletal muscle. Methods: In the present study we analyzed the changes in soleus (a red-fibre muscle) intracellular muscle content under a hyperlipidic (cafeteria) diet in Wistar rats. We also analyzed in parallel the mitochondrial content a relative index of energy output capability. Results: Cafeteria diet-fed rats contained more lipid and mitochondria per unit of muscle section area than controls. Conclusions: The correlation found in the increases of muscle lipid and mitochondria hit at this increase as an adaptation of muscle to oxidize excess energy substrates under conditions of excess energy availability, probably contributing to adaptive thermogenesis.
Subject (English)
Citation
Citation
CABOT MAJEM, Cristina, et al. Effect of cafeteria diet feeding on soleus intramyocellular lipid of Wistar rats. Journal of Endocrinology and Metabolism. 2012. Vol. 2, num. 1, pags. 21-25. ISSN 1923-2861. [consulted: 7 of June of 2026]. Available at: https://hdl.handle.net/2445/53783