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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/138618
Epigenetics in the eye: an overview of the most relevant ocular diseases
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Sight for mammals is one of the most appreciated senses. In humans there are several factors that contribute to the increment in all kind of eye diseases. This mini-review will focus on some diseases whose prevalence is steadily increasing year after year for non-genetic reasons, namely cataracts, dry eye, and glaucoma. Aging, diet, inflammation, drugs, oxidative stress, seasonal and circadian style-of-live changes are impacting on disease prevalence by epigenetics factors, defined as stable heritable traits that are not explained by changes in DNA sequence. The mini-review will concisely show the data showing epigenetics marks in these diseases and on how knowledge on the epigenetic alterations may guide therapeutic approaches to have a healthy eye.
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ALKOZI, Hanan Awad, FRANCO FERNÁNDEZ, Rafael and PINTOR, Jesús J. Epigenetics in the eye: an overview of the most relevant ocular diseases. Frontiers In Genetics. 2017. Vol. 8, num. 144. ISSN 1664-8021. [consulted: 7 of October of 2026]. Available at: https://hdl.handle.net/2445/138618