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Epigenetics in the eye: an overview of the most relevant ocular diseases

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dc.contributor.authorAlkozi, Hanan Awad
dc.contributor.authorFranco Fernández, Rafael
dc.contributor.authorPintor, Jesús J.
dc.date.accessioned2019-08-01T11:14:21Z
dc.date.available2019-08-01T11:14:21Z
dc.date.issued2017-10-12
dc.date.updated2019-08-01T11:14:21Z
dc.description.abstractSight for mammals is one of the most appreciated senses. In humans there are several factors that contribute to the increment in all kind of eye diseases. This mini-review will focus on some diseases whose prevalence is steadily increasing year after year for non-genetic reasons, namely cataracts, dry eye, and glaucoma. Aging, diet, inflammation, drugs, oxidative stress, seasonal and circadian style-of-live changes are impacting on disease prevalence by epigenetics factors, defined as stable heritable traits that are not explained by changes in DNA sequence. The mini-review will concisely show the data showing epigenetics marks in these diseases and on how knowledge on the epigenetic alterations may guide therapeutic approaches to have a healthy eye.
dc.format.extent7 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec674719
dc.identifier.issn1664-8021
dc.identifier.pmid29075285
dc.identifier.urihttps://hdl.handle.net/2445/138618
dc.language.isoeng
dc.publisherFrontiers Media
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.3389/fgene.2017.00144
dc.relation.ispartofFrontiers In Genetics, 2017, vol. 8, p. 144
dc.relation.urihttps://doi.org/10.3389/fgene.2017.00144
dc.rightscc-by (c) Alkozi, Hanan A. et al., 2017
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es
dc.sourceArticles publicats en revistes (Bioquímica i Biomedicina Molecular)
dc.subject.classificationEpigenètica
dc.subject.classificationManifestacions oculars de les malalties
dc.subject.otherEpigenetics
dc.subject.otherOcular manifestations of general diseases
dc.titleEpigenetics in the eye: an overview of the most relevant ocular diseases
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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Articles publicats en revistes (Bioquímica i Biomedicina Molecular)