Sequential ring-closing metathesis-vinyl halide Heck cyclization reactions: access to the tetracyclic ring system of ervitsine

Vista senzilla d'ítem
dc.contributor.authorBennasar Fèlix, M. Lluïsa
dc.contributor.authorZulaica Gallego, Ester
dc.contributor.authorSolé Arjó, Daniel
dc.contributor.authorAlonso Serrano, Sandra
dc.date.accessioned2020-06-04T11:38:03Z
dc.date.available2020-06-04T11:38:03Z
dc.date.issued2012-06-17
dc.date.updated2020-06-04T11:38:03Z
dc.description.abstractA chemoselective indole-templated ring-closing metathesis is used to assemble the cyclohepta[b]indole substructure of the indole alkaloid ervitsine. A subsequent intramolecular Heck coupling of the resulting alkene functionality with an amino-tethered vinyl halide accomplishes the closure of the unique 2- azabicyclo[4.3.1]decane framework of the alkaloid with concomitant incorporation of the exocyclic Eethylidene substituent.
dc.format.extent8 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idgrec622691
dc.identifier.issn0040-4020
dc.identifier.urihttps://hdl.handle.net/2445/164274
dc.language.isoeng
dc.publisherElsevier B.V.
dc.relation.isformatofVersió postprint del document publicat a:
dc.relation.ispartofTetrahedron, 2012, vol. 68, num. 24, p. 4641-4648
dc.rights(c) Elsevier B.V., 2012
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.sourceArticles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
dc.subject.classificationMetàtesi (Química)
dc.subject.classificationReaccions químiques
dc.subject.classificationProductes naturals
dc.subject.classificationSíntesi orgànica
dc.subject.classificationAlcaloides
dc.subject.otherMetathesis (Chemistry)
dc.subject.otherChemical reactions
dc.subject.otherNatural products
dc.subject.otherOrganic synthesis
dc.subject.otherAlkaloids
dc.titleSequential ring-closing metathesis-vinyl halide Heck cyclization reactions: access to the tetracyclic ring system of ervitsine
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/acceptedVersion

Fitxers

Paquet original

Mostrant 1 - 1 de 1
Miniatura
Nom:
622691.pdf
Mida:
592.55 KB
Format:
Adobe Portable Document Format
Descarregar

Col·leccions

Articles publicats en revistes (Farmacologia, Toxicologia i Química Terapèutica)
Articles publicats en revistes (Institut de Biomedicina (IBUB))