Carregant...
Miniatura

Tipus de document

Article

Versió

Versió acceptada

Data de publicació

Llicència de publicació

cc-by-nc-nd (c) Current Opinion, 2020
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/167084

Integrating the roles of liver x receptors in inflammation and infection: mechanisms and outcomes

Títol de la revista

Director/Tutor

ISSN de la revista

Títol del volum

Resum

Liver X receptors (LXRs) are transcription factors from the nuclear receptor family that can be pharmacologically activated by high-affinity agonists. LXR activation exerts a combination of metabolic and anti-inflammatory actions that result in the modulation of immune responses and in the amelioration of inflammatory disorders. In addition, LXR agonists modulate the metabolism of infected cells and limit the infectivity and/or growth of several pathogens. This review gives an overview of the recent advances in understanding the complexity of the mechanisms through which the LXR pathway controls inflammation and host-cell pathogen interaction.

Citació

Citació

GLARÍA PERCAZ, Estibaliz, LETELIER TORRES, Nicole, VALLEDOR FERNÁNDEZ, Annabel. Integrating the roles of liver x receptors in inflammation and infection: mechanisms and outcomes. _Current Opinion In Pharmacology_. 2020. Vol. 53, núm. 55-65. [consulta: 22 de gener de 2026]. ISSN: 1471-4892. [Disponible a: https://hdl.handle.net/2445/167084]

Exportar metadades

JSON - METS

Compartir registre