Amb motiu del tancament d'estiu, la validació de documents es reprendrà a partir del 28 d'agost de 2026. Disculpeu les molèsties.
Con motivo del cierre de verano, la validación de documentos se reanudará a partir del 28 de agosto de 2026. Disculpad las molestias
Due to the summer closure, document validation will resume starting August 28, 2026. We apologize for any inconvenience.

Files

667187.pdf (1.08 MB)

Document type

Article

Version

Published version

Publication date

2016-02-06

Publication license

cc-by (c) Real, Eva et al., 2016
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/113730

Removing and reimplanting deep brain stimulation therapy devices in resistant OCD (when the patient does not respond): case report

Journal Title

Authors

Director/Tutor

Journal ISSN

Volume Title

Related resource

https://doi.org/10.1186/s12888-016-0730-z

Abstract

Background: Deep brain stimulation (DBS) is emerging as a promising tool in the treatment of refractory obsessive-compulsive disorder (OCD) but the search for the best target still continues. This issue is especially relevant when particularly resistant profiles are observed in some patients, which have been ascribed to individual responses to DBS according to differential patterns of connectivity. As patients have been implanted, new dilemmas have emerged, such as what to do when the patient does not respond to surgery. Case presentation: Here we describe a 22-year-old male with extremely severe OCD who did not respond to treatment with DBS in the nucleus accumbens, but who did respond after explanting and reimplanting leads targeting the ventral capsule-ventral striatum region. Information regarding the position of the electrodes for both surgeries is provided and possible brain structures affected during stimulation are reviewed. To our knowledge this case is the first in the literature reporting the removal and reimplantation of DBS leads for therapeutical benefits in a patient affected by a mental disorder. Conclusion: The capability for explantation and reimplantation of leads should be considered as part of the DBS therapy reversibility profile in resistant mental disorders, as it allows application in cases of non-response to the first surgery.

Subject

Neurosi obsessiva, Estudi de casos, Estimulació del cervell, Terapèutica

Subject (English)

Obsessive-compulsive disorder, Case studies, Brain stimulation, Therapeutics

Citation

Collections

Articles publicats en revistes (Ciències Clíniques)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

Citation

REAL, Eva, et al. Removing and reimplanting deep brain stimulation therapy devices in resistant OCD (when the patient does not respond): case report. BMC Psychiatry. 2016. Vol. 16, num. 26. ISSN 1471-244X. [consulted: 12 of August of 2026]. Available at: https://hdl.handle.net/2445/113730

Export metadata

JSON - METS

Share record