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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/197785
Stereotactic body radiotherapy versus surgery for lung metastases from colorectal cancer: single-institution results
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Background: Surgery and stereotactic body radiotherapy (SBRT) are two of the options available as local treatments for pulmonary oligometastases from colorectal cancer (CRC). We hypothesized that SBRT would have, at least, a similar local control rate to surgery. Methods: We identified an initial cohort of 100 patients with CRC who received SBRT or surgery for lung metastases. This was then narrowed down to 75 patients: those who underwent surgery (n = 50) or SBRT (n = 25) as their first local thoracic treatment between 1 January 2004 and 29 December 2017. The Kaplan-Meier method was used to calculate lung-progression-free survival (L-PFS) and overall survival (OS). Results: The 1 and 2-year L-PFS was 85% and 70% in the surgical group and 87% and 71% in the SBRT group, respectively (p = 0.809). No significant differences were found between the two groups in terms of OS. The biologically effective dose (BED), age and initial CRC stage did not have a significant effect on local control or survival. No grade 3 or above acute- or late-toxicity events were reported. Conclusions: These results add retrospective evidence that SBRT and surgery have similar results in terms of OS and local control in patients with lung oligometastases from CRC.
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GARCIA EXPOSITO, Nerea, RAMOS IZQUIERDO, Ricard, NAVARRO PEREZ, Valentin, MOLINA, Kevin, ARNAIZ, Maria dolores, PADRONES, Susana, RUFFINELLI, José carlos, SANTOS, Cristina, GUEDEA EDO, Ferran, NAVARRO MARTÍN, Arturo. Stereotactic body radiotherapy versus surgery for lung metastases from colorectal cancer: single-institution results. _Cancers_. 2023. Vol. 15, núm. 4, pàgs. 1195. [consulta: 23 de gener de 2026]. ISSN: 2072-6694. [Disponible a: https://hdl.handle.net/2445/197785]