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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/160861
Synthesis of benzo-, pyrido-, thieno- and imidazo-fused N-hydroxy-4-oxopyrimidine-2-carboxylic acid derivatives
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Abstract
N-Hydroxy-4-oxoquinazoline-2-carboxamide derivatives (cyclic hydroxamic acids) and related pyrido- and thieno-substituted analogues, as well as a N-hydroxyhypoxanthine-2-carboxamide were synthesised for the first time, by means of a four-step sequence that involves a smooth reaction of aminohydroxamates with methyl trimethoxyacetate. Other strategies were unsuccessful.
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BOSCH HEREU, Lluís, et al. Synthesis of benzo-, pyrido-, thieno- and imidazo-fused N-hydroxy-4-oxopyrimidine-2-carboxylic acid derivatives. Tetrahedron Letters. 2011. Vol. 52, num. 7, pags. 753-756. ISSN 0040-4039. [consulted: 18 of August of 2026]. Available at: https://hdl.handle.net/2445/160861