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diagnostics-14-01424.pdf (764.45 KB)

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2024-07-03

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cc by (c) Heras, Marta et al, 2024
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/214871

Real Implication of Fertility-Sparing Surgery for Ovarian Cancer: Reproductive Outcomes

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https://doi.org/10.3390/diagnostics14131424

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Background: to prove the effectivity of fertility-sparing procedures in early-stage ovarian cancer by assessing pregnancy rates and obstetrical outcomes. Methods: we performed a retrospective multicenter study among 55 Spanish hospitals, collecting patients from 18 to 40 years old with diagnosis of early-stage ovarian cancer, epithelial (EOC) or non-epithelial (non-EOC), from January 2010 to December 2019. Data on the use of assisted reproductive techniques, pregnancy attempts and obstetrical outcomes were collected. Results: a total of 150 patients met inclusion criteria, 70 (46.6%) EOC and 80 (53.4%) non-EOC. Pregnancy attempts were reported in 51 (34%) patients, with 42 (28%) patients carrying the pregnancy to term. Among them, 30 (71.4%) underwent surgery alone and 12 (28.6%) had additional postoperative chemotherapy. A total of 32 (76.1% patients) had spontaneous pregnancies and 10 (23.9%) required in vitro fertilization. There was only one (2.4%) complication reported. Vaginal delivery was reported in twenty-nine (69%) patients and cesarean section in five (11.9%) patients. Conclusions: fertility-sparing management for ovarian cancer seems to be an option with proven good pregnancy rates and low complications. The selection of patients must consider strict criteria in order to maintain a good prognosis.

Matèries

Càncer d'ovari, Fecunditat

Matèries (anglès)

Ovarian cancer, Fertility

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Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

Citació

HERAS, Marta, ALONSO ESPIAS, Maria, ARENCIBIA, Octavio, MINIG, Lucas, MARTÍ, Lola, DIESTRO, Maria dolores, CESPEDES, Juan, NÍGUEZ, Isabel, GIL IBÁÑEZ, Blanca, DÍAZ FEIJOO, Berta, LLUECA, Antoni, ROSADO, Claudia, IACOPONI, Sara, LOPEZ DE LA MANZANARA, Carlos, MORALES, Sara, FERNÁNDEZ GALGUERA, María josé, CANO, Ana, GOROSTIDI, Mikel, ZAPARDIEL, Ignacio. Real Implication of Fertility-Sparing Surgery for Ovarian Cancer: Reproductive Outcomes. _Diagnostics_. 2024. Vol. 14, núm. 13. [consulta: 27 de gener de 2026]. ISSN: 2075-4418. [Disponible a: https://hdl.handle.net/2445/214871]

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