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Article

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Accepted version

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2013

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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/119423

Effectiveness and tolerability of duloxetine in 2 different ethnic samples: a prospective observational cohort study

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https://doi.org/10.1097/JCP.0b013e31828567d4

Abstract

Researchers have begun to study the pharmacologic properties of medications in different ethnic minority groups and national populations. In this context, delimitation of the ethnic or national category is essential to ensure sufficient cultural and genetic homogeneity to render the study meaningful. In Spain, the ''Latino'' population tends to have its origins in the Andean region of South America. There is some evidence that there is genetic variation in isoenzymes CYP2D6 and CYP1A2 1 in Amerindians, which impacts the gene that encodes the serotonin transporter, 1,2 which would appear to impact the metabolism of SSRI drugs but much less so dual-acting drugs such as duloxetine.

Subject

Antidepressius, Assaigs clínics de medicaments, Observació (Mètode d'ensenyament)

Subject (English)

Antidepressants, Drug testing, Observation (Educational method)

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Articles publicats en revistes (Psicologia Clínica i Psicobiologia)

Citation

COLLAZOS, Francisco, et al. Effectiveness and tolerability of duloxetine in 2 different ethnic samples: a prospective observational cohort study. Journal of Clinical Psychopharmacology. 2013. Vol. 33, num. 2, pags. 254-256. ISSN 0271-0749. [consulted: 15 of August of 2026]. Available at: https://hdl.handle.net/2445/119423

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