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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/181775
Impact of the SARS-CoV-2 (COVID19) pandemic on the morbidity and mortality of high risk patients undergoing surgery: a non-inferiority retrospective observational study
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Background: During the COVID-19 crisis it was necessary to generate a specific care network and reconvert operating rooms to attend emergency and high-acuity patients undergoing complex surgery. The aim of this study is to classify postoperative complications and mortality and to assess the impact that the COVID-19 pandemic may have had on the results. Methods: this is a non-inferiority retrospective observational study. Two different groups of surgical patients were created: Pre-pandemic COVID and Pandemic COVID. Severity of illness was rated according to the Diagnosis-related Groups (DRG) score. Comparisons were made between groups and between DRG severity score-matched samples. Non-inferiority was set at up to 10 % difference for grade III to V complications according to the Clavien-Dindo classification, and up to 2 % difference in mortality. Results: A total of 1649 patients in the PreCOVID group and 763 patients in the COVID group were analysed; 371 patients were matched for DRG severity score 3-4 (236 preCOVID and 135 COVID). No differences were found in relation to re-operation (22.5 % vs. 21.5 %) or late admission to critical care unit (5.1 % vs. 4.5 %). Clavien grade III to V complications occurred in 107 patients (45.3 %) in the PreCOVID group and in 56 patients (41.5 %) in the COVID group, and mortality was 12.7 % and 12.6 %, respectively. During the pandemic, 3 % of patients tested positive for Covid-19 on PCR: 12 patients undergoing elective surgery and 11 emergency surgery; there were 5 deaths, 3 of which were due to respiratory failure following Covid-19-induced pneumonia. Conclusions: Although this study has some limitations, it has shown the non-inferiority of surgical outcomes during the COVID pandemic, and indicates that resuming elective surgery is safe.
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CABALLERO MILÁN, Marta, COLOMINA SOLER, M. j. (maría josé), MARIN CARCEY, Leo a., VIGUERA FERNÁNDEZ, Laura, BAYONA DOMENGE, Roser, GARCIA BALLESTER, Sara, LÓPEZ FARRE, Albert, RUIZ BUERA, Leticia, SANZ ITURBE, Maite, ÁLVAREZ VILLEGAS, David, JENSSEN PAZ, Ely c., PUIG SANZ, Guillermo, ARCOS TERRONES, Aaron, BELMONTE CUENCA, Carmen, PERELADA ALONSO, Elia, BLASCO BLASCO, Francho, SABATÉ PES, Antoni. Impact of the SARS-CoV-2 (COVID19) pandemic on the morbidity and mortality of high risk patients undergoing surgery: a non-inferiority retrospective observational study. _BMC Anesthesiology_. 2021. Vol. 21, núm. 1, pàgs. 295. [consulta: 9 de abril de 2026]. [Disponible a: https://hdl.handle.net/2445/181775]