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Alonso-MoleroJ.pdf (1.21 MB)

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2020-11-01

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cc by (c) Alonso Molero et al., 2020
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/173797

Quality of Life in a Cohort of 1078 Women Diagnosed with Breast Cancer in Spain: 7-Year Follow-Up Results in the MCC-Spain Study

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https://doi.org/10.3390/ijerph17228411

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Breast cancer is the most frequent cause of tumors and net survival is increasing. Achieving a higher survival probability reinforces the importance of studying health-related quality of life (HR-QoL). The main aim of this work is to test the relationship between different sociodemographic, clinical and tumor-intrinsic characteristics, and treatment received with HR-QoL measured using SF-12 and the FACT/NCCN (National Comprehensive Cancer Network/Functional Assessment of Cancer Therapy) Breast Symptom Index (FBSI). Women with breast cancer recruited between 2008 and 2013 and followed-up until 2017-2018 in a prospective cohort answered two HR-QoL surveys: the SF-12 and FBSI. The scores obtained were related to woman and tumor characteristics using linear regression models. The telephone survey was answered by 1078 women out of 1685 with medical record follow-up (64%). Increases in all three HR-QoL scores were associated with higher educational level. The score differences between women with university qualifications and women with no schooling were 5.43 for PCS-12, 6.13 for MCS-12 and 4.29 for FBSI. Histological grade at diagnosis and recurrence in the follow-up displayed a significant association with mental and physical HR-QoL, respectively. First-line treatment received was not associated with HR-QoL scores. On the other hand, most tumor characteristics were not associated with HR-QoL. As breast cancer survival is improving, further studies are needed to ascertain if these differences still hold in the long run.

Matèries

Càncer de mama, Qualitat de vida

Matèries (anglès)

Breast cancer, Quality of life

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Articles publicats en revistes (Ciències Clíniques)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

Citació

ALONSO MOLERO, Jéssica, DIERSSEN SOTOS, Trinidad, GÓMEZ ACEBO, Inés, FERNÁNDEZ DE LARREA BAZ, Nerea, GUEVARA, Marcela, AMIANO, Pilar, CASTAÑO-VINYALS, Gemma, FERNÁNDEZ VILLA, Tania, MORENO AGUADO, Víctor, BAYO CALERO, Juan, MOLINA BARCELOA, Ana, FERNÁNDEZ ORTIZ, María, SUAREZ CALLEJA, Claudia, MARCOS GRAGERA, Rafael, CASTELLS, Xavier, GIL MAJUELO, Leire, ARDANAZ, Eva, PÉREZ GÓMEZ, Beatriz, KOGEVINAS, Manolis, POLLÁN, Marina, LLORCA, Javier. Quality of Life in a Cohort of 1078 Women Diagnosed with Breast Cancer in Spain: 7-Year Follow-Up Results in the MCC-Spain Study. _International Journal of Environmental Research and Public Health_. 2020. Vol. 17, núm. 22. [consulta: 25 de gener de 2026]. [Disponible a: https://hdl.handle.net/2445/173797]

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