Miniatura

Fitxers

861823.pdf (4.31 MB)

Tipus de document

Article

Versió

Versió acceptada

Data de publicació

2024-09-01

Llicència de publicació

cc-by-nc-nd (c) Elsevier B.V., 2024
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/214340

Clinical, sociodemographic and environmental predicting factors for relapse in bipolar disorder: A systematic review

Títol de la revista

Autors

Director/Tutor

ISSN de la revista

Títol del volum

Recurs relacionat

https://doi.org/10.1016/j.jad.2024.05.064

Resum

Introduction: Bipolar disorder (BD) is a chronic and recurrent illness characterized by manic, mixed or depressive episodes, alternated with periods of euthymia. Several prognostic factors are associated with higher rates of relapse, which is crucial for the identification of high-risk individuals. This study aimed at systematically reviewing the existing literature regarding the impact of sociodemographic, clinical and environmental factors, in clinical relapses, recurrences and hospitalizations due to mood episodes in BD. Methods: A systematic search of electronic databases (PubMed, Cochrane library and Web of Science) was conducted to integrate current evidence about the impact of specific risk factors in these outcomes. Results: Fifty-eight articles met the inclusion criteria. Studies were grouped by the type of factors assessed. Family and personal psychiatric history, more severe previous episodes, earlier age of onset, and history of rapid cycling are associated with clinical relapses, along with lower global functioning and cognitive impairments. Unemployment, low educational status, poorer social adjustment and life events are also associated with higher frequency of episodes, and cannabis with a higher likelihood for rehospitalization. Limitations: small sample sizes, absence of randomized clinical trials, diverse follow-up periods, lack of control for some confounding factors, heterogeneous study designs and diverse clinical outcomes. Conclusions: Although current evidence remains controversial, several factors have been associated with an impaired prognosis, which might allow clinicians to identify patients at higher risk for adverse clinical outcomes and find modifiable factors. Further research is needed to elucidate the impact of each risk factor in the mentioned outcomes.

Matèries

Trastorn bipolar, Assistència hospitalària, Factors de risc en les malalties, Pronòstic mèdic

Matèries (anglès)

Manic-depressive illness, Hospital care, Risk factors in diseases, Prognosis

Citació

Col·leccions

Articles publicats en revistes (Medicina)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

Citació

GIMÉNEZ PALOMO, Anna, ANDREU, Helena, OLIVIER, Luis, OCHANDIANO, Iñaki, DE JUAN, Oscar, FERNÁNDEZ-PLAZA, Tábatha, SALMERÓN, Sergi, BRACCO, Lorenzo, COLOMER, Lluc, MENA, Juan ignacio, VIETA I PASCUAL, Eduard, PACCHIAROTTI, Isabella. Clinical, sociodemographic and environmental predicting factors for relapse in bipolar disorder: A systematic review. _Journal of Affective Disorders_. 2024. Vol. 360, núm. 276-296. [consulta: 24 de gener de 2026]. ISSN: 0165-0327. [Disponible a: https://hdl.handle.net/2445/214340]

Exportar metadades

JSON - METS

Compartir registre