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Article

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Accepted version

Publication date

2018-12-19

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Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/189808

Mdscs in Infectious diseases: regulation, roles, and readjustment

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https://doi.org/10.1007/s00262-018-2277-y

Abstract

Many pathogens, ranging from viruses to multicellular parasites, promote expansion of MDSCs, which are myeloid cells that exhibit immunosuppressive features. The roles of MDSCs in infection depend on the class and virulence mechanisms of the pathogen, the stage of the disease, and the pathology associated with the infection. This work compiles evidence supported by functional assays on the roles of different subsets of MDSCs in acute and chronic infections, including pathogen-associated malignancies, and discusses strategies to modulate MDSC dynamics to benefit the host.

Subject

Immunosupressió, Infeccions, Virus oncogènics

Subject (English)

Immunosuppression, Infections, Oncogenic viruses

Citation

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Articles publicats en revistes (Biologia Cel·lular, Fisiologia i Immunologia)

Citation

DORHOI, Anca, et al. Mdscs in Infectious diseases: regulation, roles, and readjustment. Cancer Immunology Immunotherapy. 2018. Vol. 68, num. 4, pags. 673-685. ISSN 0340-7004. [consulted: 19 of August of 2026]. Available at: https://hdl.handle.net/2445/189808

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