Using Small Non-Coding RNAs in Extracellular Vesicles of Semen as Biomarkers of Male Reproductive System Health: Opportunities and Challenges

dc.contributor.authorLarriba, Sara
dc.contributor.authorVigués i Julià, Francesc
dc.contributor.authorBassas, Lluís
dc.date.accessioned2023-03-28T16:35:06Z
dc.date.available2023-03-28T16:35:06Z
dc.date.issued2023-03-13
dc.date.updated2023-03-28T14:51:33Z
dc.description.abstractReproductive dysfunction and urogenital malignancies represent a serious health concern in men. This is in part as a result of the absence of reliable non-invasive tests of diagnosis/prognosis. Optimizing diagnosis and predicting the patient’s prognosis will affect the choice of the most appropriate treatment and therefore increase the chances of success and the result of therapy, that is, it will lead to a more personalized treatment of the patient. This review aims firstly to critically summarize the current knowledge of the reproductive roles played by extracellular vesicle small RNA components, which are typically altered in diseases affecting the male reproductive tract. Secondly, it aims to describe the use of semen extracellular vesicles as a non-invasive source of sncRNA-based biomarkers for urogenital diseases.
dc.format.extent13 p.
dc.format.mimetypeapplication/pdf
dc.identifier.issn1422-0067
dc.identifier.pmid36982521
dc.identifier.urihttps://hdl.handle.net/2445/196115
dc.language.isoeng
dc.publisherMDPI AG
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.3390/ijms24065447
dc.relation.ispartofInternational Journal of Molecular Sciences, 2023, vol. 24, num. 6, p. 5447
dc.relation.urihttps://doi.org/10.3390/ijms24065447
dc.rightscc by (c) Larriba, Sara et al., 2023
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by/3.0/es/*
dc.sourceArticles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))
dc.subject.classificationMalalties de l'aparell genitourinari
dc.subject.classificationEsterilitat masculina
dc.subject.classificationCàncer de pròstata
dc.subject.classificationDiagnòstic
dc.subject.classificationPronòstic mèdic
dc.subject.otherGenitourinary organs diseases
dc.subject.otherMale sterility
dc.subject.otherProstate cancer
dc.subject.otherDiagnosis
dc.subject.otherPrognosis
dc.titleUsing Small Non-Coding RNAs in Extracellular Vesicles of Semen as Biomarkers of Male Reproductive System Health: Opportunities and Challenges
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

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