Human induced pluripotent stem cell-derived kidney organoids toward clinical implementations

Vista senzilla d'ítem
dc.contributor.authorGarreta, Elena
dc.contributor.authorNauryzgaliyeva, Zarina
dc.contributor.authorMontserrat Pulido, Núria
dc.date.accessioned2022-09-05T08:07:02Z
dc.date.available2022-09-05T08:07:02Z
dc.date.issued2021-12-01
dc.date.updated2022-08-22T18:25:16Z
dc.description.abstractThe generation of kidney organoids from human pluripotent stem cells (hPSCs) has represented a relevant scientific achievement in the organoid field. Importantly, hPSC-derived kidney organoids contain multiple nephron-like structures that exhibit some renal functional characteristics and have the capacity to respond to nephrotoxic agents. In this review, we first discuss how bioengineering approaches can help overcome current kidney organoid challenges. Next, we focus on recent works exploiting kidney organoids for drug screening and disease modeling applications. Finally, we provide a state of the art on current research toward the potential application of kidney organoids and renal cells derived from hPSCs for future renal replacement therapies.
dc.format.extent13 p.
dc.format.mimetypeapplication/pdf
dc.identifier.idimarina6542307
dc.identifier.issn2468-4511
dc.identifier.urihttps://hdl.handle.net/2445/188683
dc.language.isoeng
dc.relation.isformatofReproducció del document publicat a: https://doi.org/10.1016/j.cobme.2021.100346
dc.relation.ispartofCurrent Opinion in Biomedical Engineering, 2021, vol. 20, num. 100346
dc.relation.urihttps://doi.org/10.1016/j.cobme.2021.100346
dc.rightscc by-nc-nd (c) Garreta, Elena et al., 2021
dc.rights.accessRightsinfo:eu-repo/semantics/openAccess
dc.rights.urihttp://creativecommons.org/licenses/by-nc-nd/3.0/es/*
dc.sourceArticles publicats en revistes (Institut de Bioenginyeria de Catalunya (IBEC))
dc.subject.classificationEnginyeria biomèdica
dc.subject.classificationRonyó
dc.subject.classificationCèl·lules mare
dc.subject.otherBiomedical engineering
dc.subject.otherKidney
dc.subject.otherStem cells
dc.titleHuman induced pluripotent stem cell-derived kidney organoids toward clinical implementations
dc.typeinfo:eu-repo/semantics/article
dc.typeinfo:eu-repo/semantics/publishedVersion

Fitxers

Paquet original

Mostrant 1 - 1 de 1
Miniatura
Nom:
2022_CurOpiBioEng_Human_GarretaE.pdf
Mida:
914.44 KB
Format:
Adobe Portable Document Format
Descarregar

Col·leccions

Articles publicats en revistes (Institut de Bioenginyeria de Catalunya (IBEC))