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cc by-nc (c) Rodríguez de Dios, Núria et al, 2022
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/186069

GOECP/SEOR radiotheraphy guidelines for non-small-cell lung cancer

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Non-small cell lung cancer (NSCLC) is a heterogeneous disease accounting for approximately 85% of all lung cancers. Only 17% of patients are diagnosed at an early stage. Treatment is multidisciplinary and radiotherapy plays a key role in all stages of the disease. More than 50% of patients with NSCLC are treated with radiotherapy (curative-intent or palliative). Technological advances-including highly conformal radiotherapy techniques, new immobilization and respiratory control systems, and precision image verification systems-allow clinicians to individualize treatment to maximize tumor control while minimizing treatment-related toxicity. Novel therapeutic regimens such as moderate hypofractionation and advanced techniques such as stereotactic body radiotherapy (SBRT) have reduced the number of radiotherapy sessions. The integration of SBRT into routine clinical practice has radically altered treatment of early-stage disease. SBRT also plays an increasingly important role in oligometastatic disease. The aim of the present guidelines is to review the role of radiotherapy in the treatment of localized, locally-advanced, and metastatic NSCLC. We review the main radiotherapy techniques and clarify the role of radiotherapy in routine clinical practice. These guidelines are based on the best available evidence. The level and grade of evidence supporting each recommendation is provided.

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RODRÍGUEZ DE DIOS, Núria, et al. GOECP/SEOR radiotheraphy guidelines for non-small-cell lung cancer. World Journal of Clinical Oncology. 2022. Vol. 13, num. 4, pags. 237-266. ISSN 2218-4333. [consulted: 15 of June of 2026]. Available at: https://hdl.handle.net/2445/186069

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