Miniatura

Fitxers

683317.pdf (527.29 KB)

Tipus de document

Article

Versió

Versió publicada

Data de publicació

2018-08

Tots els drets reservats

Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/134069

Toxoplasmosis in transplant recipients, Europe, 2010-2014

Títol de la revista

Autors

Director/Tutor

ISSN de la revista

Títol del volum

Recurs relacionat

https://doi.org/10.3201/eid2408.180045

Resum

Transplantation activity is increasing, leading to a growing number of patients at risk for toxoplasmosis. We reviewed toxoplasmosis prevention practices, prevalence, and outcomes for hematopoietic stem cell transplant (HSCT) and solid organ transplant (SOT; heart, kidney, or liver) patients in Europe. We collected electronic data on the transplant population and prevention guidelines/regulations and clinical data on toxoplasmosis cases diagnosed during 2010-2014. Serologic pretransplant screening of allo-hematopoietic stem cell donors was performed in 80% of countries, screening of organ donors in 100%. SOT recipients were systematically screened in 6 countries. Targeted anti-Toxoplasma chemoprophylaxis was heterogeneous. A total of 87 toxoplasmosis cases were recorded (58 allo-HSCTs, 29 SOTs). The 6-month survival rate was lower among Toxoplasma-seropositive recipients and among allo-hematopoietic stem cell and liver recipients. Chemoprophylaxis improved outcomes for SOT recipients. Toxoplasmosis remains associated with high mortality rates among transplant recipients. Guidelines are urgently needed to standardize prophylactic regimens and optimize patient management.

Matèries

Toxoplasma, Antibiòtics, Paràsits, Europa

Matèries (anglès)

Toxoplasma, Antibiotics, Parasites, Europe

Citació

Col·leccions

Articles publicats en revistes (Ciències Clíniques)
Articles publicats en revistes (Institut d'lnvestigació Biomèdica de Bellvitge (IDIBELL))

Citació

ROBERT-GANGNEUX, Florence, MERONI, Valeria, DUPONT, Damien, BOTTEREL, Françoise, AGUADO, José maría, BRENIER-PINCHART, Marie-pierre, ACCOCEBERRY, Isabelle, AKAN, Hamdi, ABBATE, Isabella, BOGGIAN, Katia, BRUSCHI, Fabrizio, CARRATALÀ, Jordi, DAVID, Miruna d., DRGONA, Lubos, DJURKOVIC-DJAKOVIC, Olgica, FARIÑAS, María carmen, GENCO, Francesca, GKRANIA-KLOTSAS, Effrossyni, GROLL, Andreas h., GUY, Edward, HIRZEL, Cédric, KHANNA, Nina, KURT, Özgür, JUNIE, Lia monica, LAZZAROTTO, Tiziana, LEN, Óscar, MUELLER, Nicolas j., MUÑOZ, Patricia, PLANA, Zoi dorothea, ROILIDES, Emmanuel, STAJNER, Tijana, VAN DELDEN, Christian, VILLENA, Isabelle, PELLOUX, Hervé, MANUEL, Oriol. Toxoplasmosis in transplant recipients, Europe, 2010-2014. _Emerging Infectious Diseases_. 2018. Vol. 24, núm. 8, pàgs. 1497-1504. [consulta: 25 de febrer de 2026]. ISSN: 1080-6040. [Disponible a: https://hdl.handle.net/2445/134069]

Exportar metadades

JSON - METS

Compartir registre