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Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/68440
Extracellular vesicles in parasitic diseases
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Parasitic diseases affect billions of people and are considered
a major public health issue. Close to 400 species are estimated
to parasitize humans, of which around 90 are responsible for
great clinical burden and mortality rates. Unfortunately, they
are largely neglected as they are mainly endemic to poor
regions. Of relevance to this review, there is accumulating
evidence of the release of extracellular vesicles (EVs) in
parasitic diseases, acting both in parasite-parasite
inter-communication as well as in parasite-host interactions.
EVs participate in the dissemination of the pathogen and play a
role in the regulation of the host immune systems. Production of
EVs from parasites or parasitized cells has been described for a
number of parasitic infections. In this review, we provide the
most relevant findings of the involvement of EVs in
intercellular communication, modulation of immune responses,
involvement in pathology, and their potential as new diagnostic
tools and therapeutic agents in some of the major human
parasitic pathogens.
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MARCILLA, Antonio, et al. Extracellular vesicles in parasitic diseases. Journal of Extracellular Vesicles. 2014. Vol. 3, num. 25040. ISSN 2001-3078. [consulted: 23 of August of 2026]. Available at: https://hdl.handle.net/2445/68440