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2022-02-02

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cc-by (c) Anton, Aina et al., 2022
Please use this identifier to cite or link to this item: https://hdl.handle.net/2445/185770

The Pathophysiology of Portal Vein Thrombosis in Cirrhosis: Getting Deeper into Virchows Triad

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https://doi.org/10.3390/jcm11030800

Abstract

Portal vein thrombosis (PVT) is a common complication among patients with cirrhosis. However, its pathophysiology is not well established and there are currently very few predictive factors, none of which are actually useful, from a clinical perspective. The contribution of each of the vertices of Virchow's triad, e.g., blood hypercoagulability, blood flow, and portal vein endothelial damage in the development of PVT is not clear. In this review, we aim to recapitulate the latest studies on the field of PVT development in order to understand its mechanisms and discuss some of the future directions in the study of this important complication of cirrhosis.

Subject

Cirrosi hepàtica, Coagulació sanguínia, Trombosi, Endoteli, Vena porta, Circulació sanguínia

Subject (English)

Hepatic cirrhosis, Blood coagulation, Thrombosis, Endothelium, Portal vein, Circulation of the blood

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Articles publicats en revistes (Medicina)
Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

Citation

ANTON, Aina, et al. The Pathophysiology of Portal Vein Thrombosis in Cirrhosis: Getting Deeper into Virchows Triad. Journal of Clinical Medicine. 2022. Vol. 11, num. 3. ISSN 2077-0383. [consulted: 12 of August of 2026]. Available at: https://hdl.handle.net/2445/185770

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