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cc-by-nc-nd (c) Sociedad Española de Nefrología, 2013
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/100000

Acute renal failure induced by acute interstitial nephritis secondary to cocaine

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Cocaine has been used by 2.6% of the Spanish population aged between 15 and 64 at some point in their life, making it one of the most consumed illegal drugs after cannabis.1 Cocaine use is associated with multiple complications: neurological, cardiovascular, psychiatric, pulmonary, gastrointestinal and nephrological. Renal complications associated with cocaine use have received little attention, despite the existence of several mechanisms, in addition to secondary high blood pressure, that can cause acute renal failure (ARF) or worsen a pre-existing case of chronic renal failure. Drug-induced acute interstitial nephritis (DIAIN) represents a high percentage of acute renal failure in clinical practice. Some studies indicate that DIAIN is the lesion responsible for renal failure in about 15% of biopsies with ARF. Furthermore, in many cases of DIAIN, no biopsy is performed and diagnosis is based on clinical data and recent administration of a new drug which, as described below, is sometimes not very easy to identify.

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GELPI, Rosana, TACO, Omar, GOMÀ, Montse, TORRAS AMBRÒS, Joan, POVEDA, Rafael, ÁLVAREZ, Teresa, GRINYÓ BOIRA, Josep m., FULLADOSA, Xavier. Acute renal failure induced by acute interstitial nephritis secondary to cocaine. _Nefrología_. 2013. Vol. 33, núm. 4, pàgs. 609-611. [consulta: 21 de gener de 2026]. ISSN: 0211-6995. [Disponible a: https://hdl.handle.net/2445/100000]

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