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12474_6232107_basal_ventricular_septal_hypertrophy_in_systemic_hypertension.pdf (1.07 MB)

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Data de publicació

2020-05-01

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cc by-nc-nd (c) Loncaric et al., 2020
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/156979

Basal Ventricular Septal Hypertrophy in Systemic Hypertension

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Recurs relacionat

https://doi.org/10.1016/j.amjcard.2020.01.045

Resum

Basal septal hypertrophy (BSH) is commonly seen in patients with systemic hypertension and has been associated with increased afterload. The impact of localized hypertrophy on left ventricular (LV) and left atrial (LA) function is still unclear. Our aim is to investigate if BSH is a marker of a more pronounced impact of hypertension on cardiac function in the early stages of hypertensive heart disease. An echocardiogram was performed in 163 well-controlled hypertensive patients and 22 healthy individuals. BSH was defined by a basal-to-mid septal thickness ratio ≥1.4. LV dimensions and mass were evaluated. LV global and regional deformation was assessed by 2-dimensional (2D) speckle tracking echocardiography, and LV diastolic function by 2D and Doppler imaging. LA function was evaluated with phasic volume indices calculated from 2D and 3-dimensional volumes, as well as speckle tracking echocardiography. The population was 54% men, mean age 57 (53 to 60) years. BSH was seen in 20% (n = 32) of the hypertensive cohort. Patients with BSH showed decreased regional LV systolic deformation, impaired LV relaxation with a higher proportion of indeterminate LV diastolic function, and LA functional impairment defined by a reduction of reservoir strain and a change in LA functional dynamics. In conclusion, in well-controlled hypertension impairment of LV and LA function is present in patients with early LV remodeling and localized hypertrophy. BSH might be useful as an early marker of the burden of hypertensive heart disease.

Matèries

Hipertensió, Dilatació del cor

Matèries (anglès)

Hypertension, Enlargement of the heart

Citació

Col·leccions

Articles publicats en revistes (IDIBAPS: Institut d'investigacions Biomèdiques August Pi i Sunyer)

Citació

LONCARIC, Filip, et al. Basal Ventricular Septal Hypertrophy in Systemic Hypertension. The American Journal of Cardiology. 2020. Vol. 125, num. 9, pags. 1339-1346. ISSN 0002-9149. [consulted: 4 of August of 2026]. Available at: https://hdl.handle.net/2445/156979

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