Carregant...
Tipus de document
TesiVersió
Versió publicadaData de publicació
Si us plau utilitzeu sempre aquest identificador per citar o enllaçar aquest document: https://hdl.handle.net/2445/205444
Transanal total mesorectal excision for rectal cancer
Títol de la revista
Director/Tutor
ISSN de la revista
Títol del volum
Resum
[eng] Colorectal cancer is a major global public health issue. According to the 2018 Global Cancer Statistics, 1.8 million new cases of colorectal cancer are diagnosed worldwide, with almost 900,000 deaths per year. It is the 2nd most common malignancy worldwide in women and the 3rd in men, and the most frequent tumour-node-metastasis (TNM) stages at diagnosis are II (T3-4 node-negative disease) and III (node-positive disease). The implementation of screening programs, especially with colonoscopy, has been shown to reduce colorectal cancer incidence and mortality. However, incidence in young adults in developed countries seems to be increasing, which might be related to hereditary contribution but especially to lifestyle habits and the obesity epidemic. HYPOTHESIS: The oncological outcomes of transanal total mesorectal excision (TaTME) are, at least, similar to those of the established conventional total mesorectal excision (TME) techniques for rectal cancer, without a worsening of the functionalism and the patient’s health-related quality of life. OBJECTIVES To evaluate the impact of TaTME on the short- (histopathological) and mid-term (survival and recurrence) outcomes in patients with rectal cancer (Chapters 4, 5, and 6). To evaluate the impact of TaTME on the function and health-related quality of life among patients with rectal cancer (Chapter 7). To compare the quality of the resection in the two proposed solutions for the dilemma of minimally invasive TME: TaTME versus robotics (Chapter 8). To evaluate the effects on tissue microcirculation and surgical stress of a new CO2 insufflation system specially designed for TaTME (Chapter 9).
Descripció
Matèries
Matèries (anglès)
Citació
Citació
LACY OLIVER, Francisco de borja de. Transanal total mesorectal excision for rectal cancer. [consulta: 6 de desembre de 2025]. [Disponible a: https://hdl.handle.net/2445/205444]